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OCR: 8 Exogenous TRH, given intravenously ces a rise pharmacological dose of 200-400ug, ind ty minutes in TSH which peaks approximately twer vels, by eak TSH later and then declines, but not to basal TSH, and sixty minutes in normal subjects. OThe response to TRH is proportional to basa dded with current TSH assays, provides little id subjects, information in most cases. In hypothyr sponse is the basal TSH is elevated and the TSH n ver, to exaggerated. It is seldom necessary, how perform a TRH test in the diagnosis of hypothyroidism.